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Cardiovascular Risk and Weight Loss
Heart Health Risk Factors and Body Weight
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Cardiovascular Risk and Weight Loss - Study

Weight Loss Study Aim
To investigate relationships between changes in weight and changes in cardiovascular risk factors in adults, taking intentionality of weight loss into account.
Subjects included a total of 1773 French men and 2316 women aged 45 years and over.

Weight Loss Study Measurements
Weight, height, blood pressure, serum total cholesterol and fasting blood glucose were measured at baseline and after a 2-year follow-up. Self-reported dieting in order to lose weight, smoking status, leisure-time physical activity, health events and current treatments were assessed through questionnaires.

Weight Loss Study Results
In multivariate analyses, weight change was positively associated with changes in systolic and diastolic blood pressure and with changes in serum total cholesterol, after adjustment for age, baseline level of each cardiovascular risk factor and current treatments. For example, in men, a weight loss of 5 kg was associated with a decrease of 2.5 mmHg in systolic blood pressure and of 1.5 mmHg in diastolic blood pressure. Taking into account self-reported dieting did not modify these associations.

Weight Loss Study Conclusion
In both genders, systolic and diastolic blood pressure and serum cholesterol increased with weight gain and decreased with weight loss, independently of the intentionality to lose weight. At the population level, modest weight loss may have a substantial impact on cardiovascular risk, and preventing even modest weight gain in adults is an important goal in terms of public health.

Source: International Journal of Obesity

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