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Fen-Phen Weight Loss Appetite Suppressant Drug
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Fen Phen

Drug made of the combination of fenfluramine and phentermine for use as an appetite suppressant in the management of obesity. Also known as Fen-Phen, PhenFen, or Phen-Fen.

Fen Phen Background
From 1989 through September 1997, two prescription drugs for weight loss were sold in the United States under the brand names Pondimin (fenfluramine) and Redux (dexfenfluramine). Beginning in 1992, physicians commonly prescribed Pondimin in combination with phentermine, another prescription diet drug. Phentermine was, and still is, manufactured by various entities and is distributed and sold under several different brand names. The combination of Pondimin with phentermine was often referred to as "fen-phen." From January 1995 until September 1997 approximately four million persons in the United States took Pondimin. Similarly, from June 1986 through September 1997, two million people in this country used Redux.

Fen-Phen Drug Combination
- Health Effects

During the period from March to August 1997, the Mayo Clinic in Rochester, Minnesota observed and reported an association between the use of fenfluramine and/or dexfenfluramine and valvular heart disease ("VHD"). On September 15, 1997, the FDA announced that there would be no further sales of Pondimin and Redux in the United States. Since the withdrawal, epidemiological studies have established a causal relationship between fenfluramine and dexfenfluramine and VHD.
Epidemiological studies have also established that fenfluramine and dexfenfluramine cause a fatal disease known as primary pulmonary hypertension ("PPH").

Sources include: www.fen-phen-legal-resources.com

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