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Waist Circumference Size, Heart and Weight Loss
Effect of Weight Loss on Waist Measurement and Cardiovascular Risk Factors
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Waist Circumference Size, Heart & Weight Loss

Weight Loss Study Aim
To examine the relationship between waist circumference and cardiovascular risk factors during weight loss, and to consider possible waist reduction targets for weight management.

Weight Loss Study Design
Single strand six month Weight Study on food based diets in 110 women aged 18-68 years, and body mass index > or = 25 kg/m2 set at an outpatient clinic. Measurements included waist circumference, weight, body mass index (BMI), total plasma cholesterol, low (LDL) and high density lipoprotein (HDL) cholesterol, triglyceride, and blood pressure.

Weight Loss Study Results
Anthropometric and metabolic measurements improved with mean weight loss of 4.9 kg at three months and 6.2 kg at six months. Weight loss closely related to waist reduction The proportion of subjects with waist circumference below Action Level 1 (< 80 cm) or above Action Level 2 (> or = 88 cm) were 9 and 60 percent at baseline, 29 and 38 percent at three months and 36 and 33 percent at six months. Waist reduction (adjusted for age, smoking, alcohol consumption, diet treatment and baseline dependent and independent variables) correlated significantly with falls in total cholesterol , LDL cholesterol and diastolic blood pressure, but not significantly with HDL cholesterol, triglyceride or systolic blood pressure. BMI showed similar correlations, whereas waist to hip ratio changes were not associated with changes in any cardiovascular risk factors. Amongst those whose waist fell by > or = 5 cm, 45 at three months and 43 at six months, there were > or = 10 percent improvements in at least one risk factor for 71 and 84 percent respectively. Amongst those whose waist fell by 5-10 cm, 40 women at three months and 30 at six months, at least one risk factor improved by > or = 10 percent in 70 percent and in 83 percent respectively.

Weight Loss Study Conclusions
Waist reduction of 5-10 cm in Caucasian women, across a range of baseline BMI 25-50 kg/m2 or waist circumference 72-133 cm, may be used as guideline to encourage overweight women to achieve a realistic target with a high probability of health benefits.

Source: Han TS, Richmond P, Avenell A, Lean ME. Department of Human Nutrition, University of Glasgow, Glasgow Royal Infirmary, USA.

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